A deafness-associated mitochondrial DNA mutation caused pleiotropic effects on DNA replication and tRNA metabolism 2022-09-08 Long Noncoding RNA MIR4435-2HG Suppresses Colorectal Cancer Initiation and Progression By Reprogramming Neutrophils 2022-09-08 Msx1+ stem cells recruited by bioactive tissue engineering graft for bone regeneration 2022-09-08 Structure and mechanism for streptococcal fatty acid kinase (Fak) system dedicated to host fatty acid scavenging 2022-09-02 High-efficient engineering of osteo-callus organoids for rapid bone regeneration within one month 2022-08-24 Krüppel-like factor 5 rewires NANOG regulatory network to activate human naïve pluripotency specific LTR7Ys and promote naïve pluripotency 2022-08-24 Structures and mechanisms of the Arabidopsis auxin transporter PIN3 2022-08-03 Biomacromolecule based agent for high-precision light-based 3D hydrogel bio-printing 2022-07-29 Construction of the axolotl cell landscape using combinatorial hybridization sequencing at single cell resolution 2022-07-29 Structural basis of AlpA-dependent transcription antitermination 2022-07-29 BAF60a Deficiency in Macrophage Promotes Diet-Induced Obesity and Metabolic Inflammation 2022-07-18 Three enigmatic BioH isoenzymes are programmed in the early stage of mycobacterial biotin synthesis, an attractive anti-TB drug target 2022-07-13 Systematic identification of cell-fate regulatory programs using a single-cell atlas of mouse development 2022-07-13 Atlas of currently-available human neutralizing antibodies against SARS-CoV-2 and escape by Omicron sub-variants BA.1/ BA.1.1/BA.2/BA.3 2022-07-08 Phase separation of Insulin Receptor Substrate 1 drives the formation of insulin/IGF-1 signalosomes 2022-06-30 Recruitment of tetraspanin TSP-15 regulates plasma membrane repair in C. elegans epidermis 2022-06-30 Inhibition of the CDK2 and Cyclin A complex leads to autophagic degradation of CDK2 in cancer cells 2022-06-22 Ursodeoxycholic acid reduces antitumor immunosuppression by inducing CHIP-mediated TGF-β degradation 2022-06-16 m6Am Methyltransferase PCIF1 is Essential for Aggressiveness of Gastric Cancer Cells by Inhibiting TM9SF1 mRNA Translation 2022-06-07 Structures of a Mammalian TRPM8 in Closed State 2022-06-07 
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